Compare and contrast the roles of the parasympathetic and sympathetic divisions of the ANS.
The parasympathetic division is the "rest and digest" system, conserving energy and directing housekeeping activities such as digestion, defecation, and urination. The sympathetic division is the "fight or flight" system, mobilizing the body for activity and emergencies by increasing heart rate, dilating airways, and releasing glucose. The two divisions generally innervate the same visceral organs but produce opposite effects, and both are usually partially active, creating a dynamic antagonism that precisely controls visceral function.
The parasympathetic and sympathetic divisions are the two arms of the ANS, serving complementary but typically opposite roles. The parasympathetic division promotes maintenance functions and conserves body energy, acting as the "rest and digest" division; its activity is seen in relaxed states with low normal heart rate and blood pressure, an actively digesting gastrointestinal tract, constricted pupils, and lenses accommodated for close vision. The sympathetic division, sometimes called the "fight or flight" division, mobilizes the body during exercise, excitement, emergencies, and embarrassment; it produces a rapidly pounding heart, deep breathing, dilated pupils, shunting of blood to active skeletal muscles and the vigorously working heart, bronchiolar dilation, liver glucose release, and reduced gastrointestinal motility. Anatomically, the parasympathetic division is craniosacral, with long preganglionic and short postganglionic fibers and terminal ganglia within or near the visceral effector organ. The sympathetic division is thoracolumbar, with short preganglionic and long postganglionic fibers and ganglia close to the spinal cord. All parasympathetic fibers release acetylcholine, and most sympathetic postganglionic fibers release norepinephrine, though those serving sweat glands release ACh; the adrenal medulla releases epinephrine and norepinephrine that augment sympathetic effects. Because most visceral organs receive dual innervation, the divisions continuously adjust activity. Sympathetic tone keeps blood vessels partially constricted at rest, while parasympathetic tone normally dominates the heart and the digestive and urinary tract organs. The two divisions also cooperate, as in the sexual response, where parasympathetic action causes erection of the penis or clitoris and sympathetic action causes ejaculation or reflex vaginal contractions.
Key points
- Parasympathetic = "rest and digest"; conserves energy, oversees digestion, defecation, diuresis, and close-vision focusing. Sympathetic = "fight or flight"; handles exercise, excitement, and emergencies.
- Parasympathetic is craniosacral, has long preganglionic and short postganglionic fibers, and terminal ganglia within or near the target. Sympathetic is thoracolumbar, has short preganglionic and long postganglionic fibers, and ganglia near the spinal cord.
- All parasympathetic fibers release ACh (cholinergic). Sympathetic preganglionic fibers also release ACh, but most sympathetic postganglionic fibers release norepinephrine (adrenergic), except for sweat glands, which receive ACh.
- Most visceral organs are dually innervated and the two divisions are usually both partially active, creating dynamic antagonism and enabling fine-tuned control. Sympathetic tone dominates blood vessels; parasympathetic tone dominates heart, digestive, and urinary tract activity.
- The same neurotransmitter can excite or inhibit depending on the receptor subtype, with nicotinic and muscarinic ACh receptors and alpha/beta adrenergic receptors. This helps explain opposite organ responses to the two divisions.
- The divisions rarely act entirely in all-or-none fashion and occasionally cooperate, as in the external genitalia, where parasympathetic stimulation causes erection and sympathetic stimulation produces ejaculation or reflex vaginal contractions.
Related questions
- What are the three key anatomical differences between the sympathetic and parasympathetic divisions of the autonomic nervous system?
- Why does sympathetic activation produce longer-lasting effects than parasympathetic activation?
- What are the three possible pathways a preganglionic sympathetic axon can take after reaching a trunk ganglion?
- Which cranial nerves carry parasympathetic preganglionic fibers, and what is the distribution of these fibers?
- How does the sympathetic innervation of the adrenal medulla differ from typical sympathetic pathways, and why is the adrenal medulla considered a 'misplaced' sympathetic ganglion?
- What is autonomic dysreflexia and what triggers it?
Anatomy Physiology by Elaine N. Marieb, Katja N. Hoehn
Elaine N. Marieb and Katja Hoehn
Sixth Edition