What are the three possible pathways a preganglionic sympathetic axon can take after reaching a trunk ganglion?
A preganglionic sympathetic axon can synapse in the same trunk ganglion, at the same level. It can ascend or descend the sympathetic trunk to synapse in a trunk ganglion at a higher or lower level. Or it can pass through the trunk ganglion without synapsing, travel via splanchnic nerves, and synapse in a distant collateral (prevertebral) ganglion.
The three pathways are defined by where the preganglionic fiber synapses with a postganglionic neuron. First, it may synapse in the same trunk ganglion it entered, meaning the synapse occurs at the same spinal cord level. Second, it may travel up or down the sympathetic trunk and synapse in a trunk ganglion at a different level. Third, it may pass through the trunk ganglion without any synapse there, emerge as part of a splanchnic nerve, and synapse in a collateral ganglion located anterior to the vertebral column.
Key points
- Synapse in the same trunk ganglion at the same level.
- Ascend or descend the sympathetic trunk and synapse in a trunk ganglion at a higher or lower level.
- Pass through the trunk ganglion without synapsing and synapse in a distant collateral ganglion via splanchnic nerves.
Related questions
- What are the three key anatomical differences between the sympathetic and parasympathetic divisions of the autonomic nervous system?
- Why does sympathetic activation produce longer-lasting effects than parasympathetic activation?
- Which cranial nerves carry parasympathetic preganglionic fibers, and what is the distribution of these fibers?
- How does the sympathetic innervation of the adrenal medulla differ from typical sympathetic pathways, and why is the adrenal medulla considered a 'misplaced' sympathetic ganglion?
- What is the difference between the roles of the hypothalamus and the brain stem reticular formation in autonomic control?
- What is autonomic dysreflexia and what triggers it?
Anatomy Physiology by Elaine N. Marieb, Katja N. Hoehn
Elaine N. Marieb and Katja Hoehn
Sixth Edition