Mosbys 2021 Nursing Drug Reference by Linda Skidmore-Roth
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THIRTY-FOURTH EDITION
About this book
Increasingly, patients are relying on nurses to know every detail of health care. More important, nurses are expected to have these answers, especially when it comes to medication. Let Mosby’s 2021 Nursing Drug Reference be your answer. Our indis- pensable, yet compact, resource contains hundreds of monographs with several easy- to-use features.
NEW FEATURES This edition features:
- Over 30 recent FDA-approved drugs located in Appendix A (see Contents for a complete list). Included are monographs for: esketamine, for depression lefamulin, for pneumonia selinexor, for complicated cases of multiple myeloma
- An ebook with easy-to-use navigation for quick access to monographs of your choice
NEW FACTS This edition features more than 2000 new drug facts, including:
- New drugs and dosage information
- Newly researched side effects and adverse reactions
- New and revised Black Box Warnings
- The latest precautions, interactions, and contraindications
- IV therapy updates
- Revised nursing considerations
- Updated patient/family teaching guidelines
- Updated BEERS information
ORGANIZATION This reference is organized into two main sections:
- Individual drug monographs (in alphabetical order by generic name)
- Appendixes (identified by the wide thumb tabs on the edge)
The guiding principle behind this book is to provide fast, easy access to drug infor- mation and nursing considerations. Every detail, the paper, typeface, cover, binding, use of color, and appendixes, has been carefully chosen with the user in mind.
INDIVIDUAL DRUG MONOGRAPHS This book contains monographs for more than 1300 generic and 4500 trade medica- tions. Common trade names are given for all drugs regularly used in the United States and Canada, with drugs available only in Canada identified by a maple leaf .
The following information is provided, whenever possible, for safe, effective admin- istration of each drug:
High-alert status: Identifies high-alert drugs with a label and icon. Visit the Institute for Safe Medication Practices (ISMP) at http://www.ismp.org/tools/highalert medications.pdf for a list of medications and drug classes with the greatest potential for patient harm if they are used in error.
Tall man lettering: Uses the capitalization of distinguishing letters to avoid medica- tion errors and is required by the FDA for drug manufacturers.
Pronunciation: Helps the nurse master complex generic names. Rx/OTC: Identifies prescription or over-the-counter drugs. Functional and chemical classifications: Allow the nurse to see similarities and dissimilarities among drugs in the same functional but different chemical classes.
Do not confuse: Presents drug names that might easily be confused within each appropriate monograph.
Action: Describes pharmacologic properties concisely. Uses: List the conditions the drug is used to treat. Unlabeled uses: Describe drug uses that may be encountered in practice but are not yet FDA approved.
Dosages and routes: List all available and approved dosages and routes for adult, pediatric, and geriatric patients.
Available forms: Include tablets, capsules, extended-release, injectables (IV, IM, SUBCUT), solutions, creams, ointments, lotions, gels, shampoos, elixirs, suspensions, suppositories, sprays, aerosols, and lozenges.
Side effects: Groups these reactions by body system, with common side effects italicized and life-threatening reactions (those that are potentially fatal and/or perma- nently disabling) in red type for emphasis. It is important to note that in some electronic versions of Mosby’s 2021 Nursing Drug Reference, the red type may ap- pear as black, bold print.
Contraindications: List conditions under which the drug absolutely should not be given.
Precautions: List conditions that require special consideration when the drug is prescribed.
Black Box Warnings: Identify FDA warnings that highlight serious and life- threatening adverse effects.
Pharmacokinetics: Outline metabolism, distribution, and elimination. Interactions: Include confirmed drug interactions, followed by the drug or nutrient causing that interaction, when applicable.
Drug/herb: Highlights potential interactions between herbal products and prescrip- tion or OTC drugs.
Drug/food: Identifies many common drug interactions with foods. Drug/lab test: Identifies how the drug may affect lab test results. Nursing considerations: Identify key nursing considerations for each step of the nursing process: Assess, Administer, Evaluate, and Teach Patient/Family. Instructions for giving drugs by various routes (e.g., PO, IM, IV) are included, with route subhead- ings in bold.
Compatibilities: List syringe, Y-site, and additive compatibilities and incompatibili- ties.
Questions & Answers from this book
Questions and answers are connected to the referenced book and its available source material.
Chapter 1: Individual Drug Monographs
How should adenosine be administered for converting paroxysmal supraventricular tachycardia in adults and children over 50 kg?
Adenosine should be administered as a rapid intravenous (IV) bolus of 6 mg for adults and children over 50 kg. If conversion to normal sinus rhythm does not occur within 1-2 minutes, a second dose of 12 mg may be given, and this can be repeated again if necessary.
How should amphotericin B lipid complex be administered according to Mosby's 2021 Nursing Drug Reference?
Amphotericin B lipid complex should be administered intravenously (IV) at a dose of 5 mg/kg/day. It is important to give the product only after culture and sensitivity (C&S) confirm the organism and ensure it is needed to treat a life-threatening infection.
Chapter A: Selected New Drugs
What are the dosage recommendations for administering risankizumab to adults weighing 60 to 99 kg?
For adults weighing 60 to 99 kg, the recommended dosage of risankizumab is an initial subcutaneous dose of 150 mg (administered as two 75 mg injections) at weeks 0 and 4, followed by maintenance doses every 12 weeks thereafter.
How should bremelanotide (Vyleesi) be administered to premenopausal women?
Bremelanotide (Vyleesi) should be administered subcutaneously at a dose of 1.75 mg, at least 45 minutes before anticipated sexual activity. It is important not to exceed one dose in a 24-hour period and no more than eight doses in a month.
Chapter B: Ophthalmic, Nasal, Topical, and Otic Products
What are the uses of carbonic anhydrase inhibitors in ophthalmic treatment?
Carbonic anhydrase inhibitors are used in ophthalmic treatment primarily for open-angle glaucoma and ocular hypertension. They work by decreasing aqueous humor production, which helps lower intraocular pressure.
What are the common side effects associated with topical antifungals listed in the chapter?
Common side effects associated with topical antifungals include burning, stinging, dryness, and local irritation.
What are the common side effects associated with the use of ophthalmic anesthetics listed in the chapter?
Common side effects associated with ophthalmic anesthetics include burning, stinging, and dryness of the eye area.
Chapter INDEX: Index
What are the nursing considerations for administering clotrimazole for vaginal candidiasis?
Nursing considerations for administering clotrimazole for vaginal candidiasis include assessing for allergic reactions, teaching proper application techniques, and advising patients to abstain from sexual intercourse during treatment. It is also important to instruct patients on hand hygiene and to notify the prescriber if symptoms persist.
What are the nursing considerations for administering topical anesthetics like benzocaine and lidocaine?
Nursing considerations for administering topical anesthetics like benzocaine and lidocaine include assessing for allergic reactions, ensuring proper application techniques, and instructing patients on hygiene practices. It is important to avoid contact with eyes and to monitor for signs of infection before use.
What are the contraindications for using terconazole in patients?
The contraindications for using terconazole include hypersensitivity to the drug and use in children under 2 years of age. Precautions should be taken during pregnancy and breastfeeding.
Chapter C: Vaccines and Toxoids
What is the dosage schedule for the anthrax vaccine BioThrax for pre-exposure prophylaxis in adults?
The dosage schedule for the anthrax vaccine BioThrax for pre-exposure prophylaxis in adults is 0.5 mL administered subcutaneously at 0, 2, and 4 weeks, followed by additional doses of 0.5 mL at 6, 12, and 18 months.
How is the Japanese encephalitis virus vaccine administered to adults and children over 3 years?
The Japanese encephalitis virus vaccine is administered to adults and children over 3 years as an intramuscular injection of 0.5 mL in the deltoid muscle, followed by a second dose of 0.5 mL 28 days later.
What are the contraindications for administering the dengue tatravalent vaccine, live Dengvaxia?
The contraindications for administering the dengue tatravalent vaccine, live Dengvaxia, include hypersensitivity.
Chapter D: Recent FDA Drug Approvals
What are the side effects associated with buPROPion as mentioned in the chapter?
The side effects associated with buPROPion include common effects such as insomnia, dry mouth, and increased sweating. Life-threatening effects can include seizures and an increased risk of suicidal thoughts or behaviors.
Which drugs are indicated for the treatment of chronic obstructive pulmonary disease (COPD) according to the recent FDA drug approvals chapter?
Drugs indicated for the treatment of chronic obstructive pulmonary disease (COPD) include aclidinium, aclidinium/formoterol, albuterol, arformoterol, fluticasone, fluticasone/salmeterol, formoterol, hydrocortisone, indacaterol, ipratropium, revefenacin, roflumilast, salmeterol, and tiotropium.
Which drugs are associated with the treatment of breast cancer according to the recent FDA drug approvals?
The drugs associated with the treatment of breast cancer according to recent FDA drug approvals include fam-trastuzumab deruxtecan-nxki (Enhertu) and abemaciclib, among others.
More questions
What are the contraindications for abacavir as listed in Mosby's 2021 Nursing Drug Reference?
The contraindications for abacavir include hypersensitivity, moderate to severe hepatic disease, and lactic acidosis. Additionally, it is cautioned against in patients with HLA B5701 positivity, abrupt discontinuation, and those with severe renal disease or impaired hepatic function.
What is the recommended dosage and administration route for abaloparatide in postmenopausal women with osteoporosis?
The recommended dosage of abaloparatide for postmenopausal women with osteoporosis at high risk for fracture is 80 mcg administered subcutaneously once daily.
How should acetylcysteine be administered for acetaminophen toxicity according to the chapter?
Acetylcysteine should be administered orally at a dose of 140 mg/kg initially, followed by 70 mg/kg every 4 hours for a total of 17 doses. Alternatively, it can be given intravenously as a loading dose of 150 mg/kg over 60 minutes, followed by 50 mg/kg over 4 hours, and then 100 mg/kg over 16 hours.
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